Surveys and Hormone Monitoring

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Surveys

Contraception Database Survey

Because all contraceptives used in wildlife must be considered experimental, it is critical that records be kept on each method used, dose, date started, date ended, presence of opposite-sex in group, signs of estrous behavior, birth dates of any offspring born, abortions, date of death if an individual dies during treatment, and any other pertinent observations. Records must be included annually in the AZA Wildlife Contraception Center Survey. The resulting data will form the basis of the FDA reports and of Wildlife Contraception Center Recommendations. Failure to submit the Annual Survey will result in suspension from the trials. Each year a survey form is mailed to every institution requesting information from the previous year. Those for the MGA feed program will be mailed twice a year. Annual Survey reports should be returned to:

Sally Boutelle, Program Coordinator
AZA Wildlife Contraception Center
Saint Louis Zoo
1 Government Drive
St. Louis, MO 63110 USA
314-646-4595; Fax: 314-646-5534
Contraception@stlzoo.org

Pathology Database Survey

Dr. Linda Munson continues to conduct comprehensive pathologic examinations on reproductive tracts to detect deleterious effects associated with contraceptives. The results of these analyses become part of the AZA Wildlife Contraception Center Pathology Database and provide important information about contraceptive safety that is used to make informed decisions for our annual Recommendations. The data are also used for FDA reporting. Complete reproductive tracts are needed from BOTH CONTRACEPTED AND NON-CONTRACEPTED animals, so that we can determine if diseases are spontaneous in a species or caused by the contraceptive. We are requesting complete reproductive tracts and liver samples from CARNIVORES, MARSUPIALS, PRIMATES, MARINE MAMMALS, AND UNGULATES. Tissue collected by ovariohysterectomy or at necropsy are appropriate.
Tissue submission instructions - All reproductive tracts and other tissue samples must be prepared using the following instructions. A brief summary of the reproductive history of each animal should be included. Pathology evaluations will be conducted free of charge and a report will be sent to the contributing institution for the animal's medical records and to Dr. Ed Plotka for inclusion in the FDA reports. For institutions with their own pathologist, please contact Dr. Munson concerning the sharing of tissues for this study. This submission form also contains a request for any adverse reactions due to contraception. The Adverse Reactions Report must be filled out and submitted to the address below when diagnosis is made. Please send tissues and reports accompanied by the Tissue Submission Form to:

Linda Munson, DVM, PhD
VM -Pathology Microbiology & Immunology
4206 Vet Med 3A
One Shields Ave
Davis, CA 95616
530- 754 7963; Fax 530 752 3349

Hormone Monitoring

Monitoring hormones is a useful tool to aid in contraception. By analyzing hormone assays efficacy can be measured revealing to the WCC and the institution details on suppression. Reversibility can also be tracked through hormones. Though hormone monitoring is not required with contraception treatment it is encouraged. For more information on hormone monitoring at the Saint Louis Zoo click here.